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Image Search Results
Journal: Cancer medicine
Article Title: Anti-tumor effects of a nonsteroidal anti-inflammatory drug zaltoprofen on chondrosarcoma via activating peroxisome proliferator-activated receptor gamma and suppressing matrix metalloproteinase-2 expression.
doi: 10.1002/cam4.1438
Figure Lengend Snippet: Figure 3. (A) Cell migration assay was carried out using PPARγ knockdown cell lines, OUMS27shPPAR and SW1353shPPAR, and the control cell lines, OUMS27shNTC and SW1353shNTC with or without the treatment of zaltoprofen. A selective inhibitor of MMP2, ARP100, was used at 25 μmol/L. Scale bar = 100 μm. (B, C) The fielded wound area (%) was calculated in OUMS27 (B) and SW1353 cells (C). Values represented as the mean ± SEM. Asterisks denote a statistically significant difference (*P < 0.05 and **P < 0.01).
Article Snippet: Zaltoprofen and ARP100, a
Techniques: Cell Migration Assay, Knockdown, Control
Journal: Cancer medicine
Article Title: Anti-tumor effects of a nonsteroidal anti-inflammatory drug zaltoprofen on chondrosarcoma via activating peroxisome proliferator-activated receptor gamma and suppressing matrix metalloproteinase-2 expression.
doi: 10.1002/cam4.1438
Figure Lengend Snippet: Figure 4. (A) Cell invasion assay was carried out using a PPARγ knockdown cell line SW1353shPPAR and the control cell line SW1353shNTC with or without the treatment of zaltoprofen. A selective inhibitor of MMP2, ARP100, was used at 25 μmol/L. Scale bar = 100 μm. (B) Relative invaded cell number was calculated. Values represented as the mean ± SEM. Asterisks denote a statistically significant difference (**P < 0.01). (C) Gelatin zymography. Effects of zaltoprofen (400 μmol/L) on MMP2 activities in PPARγ knockdown cell lines, OUMS27shPPAR and SW1353shPPAR, and the control cell lines, OUMS27shNTC and SW1353shNTC.
Article Snippet: Zaltoprofen and ARP100, a
Techniques: Invasion Assay, Knockdown, Control, Zymography
Journal: Cancer medicine
Article Title: Anti-tumor effects of a nonsteroidal anti-inflammatory drug zaltoprofen on chondrosarcoma via activating peroxisome proliferator-activated receptor gamma and suppressing matrix metalloproteinase-2 expression.
doi: 10.1002/cam4.1438
Figure Lengend Snippet: Figure 6. Histopathological findings of the tumors at the second operation (preadministration of zaltoprofen, Pre) and the final operation (postadministration of zaltoprofen, Post). Scale bar = 25 μm. (A) HE staining. (B, C) Immunofluorescent stainings for PPARγ (B) and MMP2 (C). DAPI, a nuclear staining.
Article Snippet: Zaltoprofen and ARP100, a
Techniques: Staining